Expectant management for multiple pregnancy with single fetal death in second or the third trimester

Most of the stage III/ IV endometriosis patients'attempted expectant management longer than they had been advised.

大多数子宫内膜异位III/IV期患者期待疗法多于他们被建议的。

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To know the cause and the expectant management of the placenta previa, 28 cases of these diseases were analysed.

对28例前置胎盘综合征进行临床分析，旨在了解其发生因素及期待治疗的情况。

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Expectant management should not be used in clinical practice.

期待治疗成功率低不宜推广应用。

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Analysis of Pregnancy Rate with Expectant Management and Controlled Ovary Hyperstimulation Treatment in Endometriosis-associated Infertility Patients after Laparoscopic Treatment

子宫内膜异位症合并不孕患者期待处理后妊娠与控制性药物刺激卵巢后妊娠情况分析

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The success rate of conservative surgery expectant management reached 100.0% and medical treatment with a variety of choices around 80.0%~ 85.%.

保守性手术成功率100.0%。药物保守治疗方式多样，成功率约80.0%～85.0%左右。

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Intrauterine insemination with controlled ovarian hyperstimulation versus expectant management for couples with unexplained subfertility and an intermediate prognosis: a randomised clinical trial

不明原因生育能力低下且妊娠预测为中等水平的夫妇在控制性超排卵下的宫内人工受精与期待疗法的疗效比较：一项随机临床试验

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⑵ Maternal PAPP-A, maternal PAPP-A combined with maternal age and paternal age, and maternal age would respectively detect 60%, 80% and 50% of Down's syndrome fetuses with a false positive rate of 5%.

当假阳性率为5%时，单项母体血清PAPP-A、单项孕妇年龄、母体血清PAPP-A联合孕妇年龄及丈夫年龄筛查唐氏综合征胎儿的灵敏度分别为60%、50%、80%。

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Objective To investigate the effect of screening for Down syndrome ( DS) by detecting serum AFP and F-β hCG in pregnant women ( 14 to 20 weeks).

目的探讨孕中期妇女（14～20周）外周血甲胎蛋白（AFP）和游离β绒毛膜促性腺激素（F-βhCG）在胎儿唐氏综合征产前筛查中的作用。

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In DS critical region, the increase of genes causing overexpression of its product is considered to be the reason causing clinical manifestations of DS.

在唐氏综合征关键区上的基因数量的增加从而引起其产物的过度表达被认为是引起DS临床表现的原因。

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Excess of the above genes may explain some of the changes, while the other unrecognized genes in Down syndrome critical region ( DSOR) may be involved in the disease process of DS.

上述基因的过量可能解释了其中的一些变化，但唐氏综合征关键区（DSOR）上的其他未被认识的基因也可能涉及了DS的疾病过程。

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Objective: To pick out Down's syndrome and abnormal fetus of inborn neural tube defect, and reduce the birth of con-genital defect fetus through biochemical indicator detection of pregnancy serum markers.

目的通过母血清标记物生化指标检测，达到检出唐氏综合征（DS）及先天性神经管缺陷（NTD）异常胎儿，减少先天性缺陷胎儿的出生。

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Detection of Down syndrome by the double chromatography fluorescence quantitative polymerase chain reaction

双色荧光定量PCR快速诊断唐氏综合征

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Survival in infants with Down syndrome, Metropolitan Atlanta, 1979-1998

通过Metropolitan Atlanta评估的1979&1998年唐氏综合征患儿的存活情况

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Methods: MEIA was used to detect the maternal serum markers of 3,000 women with second trimester gestation-a-fetoprotein ( AFP), free B-chorionic gonadotropin ( B-hCG), in order to prenatal screen for Down syndrome.

方法：采用磁性分离酶免疫测定技术检测3000例孕中期母血清标记物&甲胎蛋白（AFP）、游离β-绒毛促性腺激素（β-hCG），筛查唐氏综合征胎儿。

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Colonic necrosis because of strangulated recurrent Morgagni's hernia in a child with Down's syndrome

唐氏综合征患儿由于反复的绞窄性Morgagni疝所导致的结肠坏死

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Objective: To improve the screening rate of Down ′ s Syndrome ( DS) by combination of ultrasonic B examination in early pregnancy and serologic analysis in middle pregnancy.

目的联合孕早期B超及孕中期母血清检测，提高对唐氏综合征（Down′s Syndrome，DS）患儿的筛查率。

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Objective: To investigate the expression level of genes located in chromosome 21 in the brain tissues of Down syndrome ( DS).

目的分析唐氏综合征（Down syndrome，DS）胎儿脑组织21号染色体（Chr21）基因的表达，探讨DS脑病变的分子机制。

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Conclusion: FISH is a valuable technique for diagnosing Down's syndrome with the merits of fast, high sensitivity, strong signal, low background, vividness and safety. Therefore, FISH technique can find wide application in the diagnosis of clinical genetic disease.

结论：荧光原位杂交技术检测唐氏综合征具有快速、敏感度高、信号强、背景低、直观安全等优点，故FISH技术在临床遗传病检测领域中具有重要的应用价值和发展前景。

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Summary ROC Curve And its Application to Evaluation of Prenatal Screening of Down's Syndrome

SROC曲线方法及其在唐氏综合征筛查试验评价中的应用

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Conclusion Real-time FQ-PCR is a reliable method that may provide a new way for non-invasive prenatal diagnosis and preimplantation genetic diagnosis for Down's syndrome.

结论实时荧光定量PCR是一种可信的诊断方法，为唐氏综合征的无创性产前诊断及植入前遗传学诊断等提供了新的思路。

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