Therapeutic effect of promoting hepatocyte growth factor on streptozocin induced diabetic rats

Objective : To investigate the establishment of rapid diabetic experimental models in SD rats with streptozotocin ( STZ ).

目的: 探讨链脲佐菌素诱导速发型SD大鼠 实验性 糖尿病模型的建立.

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Conclusion: CSMH may inhibit non-enzymatic glycation and vascular dysfunction in kidney of STZ-induced diabetic rat.

结论: 酸味中药复方对糖尿病大鼠肾的 非 酶糖化反应和血管病变有一定的抑制作用.

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Conclusion: CSMH has the function of correcting the confusion of metabolism in STZ-induced diabetic rat.

结论: 酸味中药复方对纠正糖尿病大鼠代谢紊乱一定的作用.

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DiscussionThe STZ rat model is used commonly experimental diabetic ani-mal model.

STZ大鼠模型是普遍采用的实验性糖尿病动物模型.

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Generally, the GPCP has an overestimating trend in rainfall rates.

总体上GPCP有过高估计降水率的趋势。

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That year, spring, summer, autumn GPCP data can be a very good characterization of precipitation, but the result of the winter was poor.

证明年、春、夏、秋季GPCP数据均能很好地表征流域的降水变化，但是冬季的结果较差。

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Each group was sacrificed at intervals of4 weeks and8 weeks respectively, measuring the motor nerve conduction velocities ( MNCV), conducting microscopic examination and axon video analysis.

各组分别于术后第4、8周行运动神经传导速度、形态学及图像分析等测定各项指标。

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Applications of MNCV Tests for Medicolegal Expertise of Ulnar Nerve Injury

MNCV检验在尺神经损伤法医学鉴定中的应用

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Methods The electromyography ( EMG), motor nerve conduction velocity ( MNCV), F wave conduction velocity ( FWCV) and somatosensory evoked potential ( SEP) were examined in 97 cases of cervical radicular spondylosis, and were compared with 50 normal persons.

方法对97例神经根型颈椎病患者进行肌电图（EMG）、运动神经传导速度（MNCV）、F波传导速度（FWCV）和体感诱发电位（SEP）检测，并与50名正常人组对比。

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Post therapeutic denervated potential, motor nerve conduction velocity ( MNCV) and sensory nerve conduction velocity ( SNCV) were significantly improved compared with that of before therapy.

治疗后失神经电位，运动神经传导速度，感觉神经传导速度均较治疗前有明显改善。

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Nerve electrophysiological data changes: Month 2 and 3, SNCV, MNCV and EPA were significantly higher in methylcobalamin+ insulin treated group 1 than in insulin treated group 1 ( P < 0.05);

神经电生理指标变化病程2和3个月时，甲钴胺+胰岛素治疗1组感觉和运动神经传导速度及波幅明显高于胰岛素治疗1组同期（P<0.05）；

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MNCV was faster in the exercise group than that in the model group ( P < 0.05) at the 4th week post-operation.

术后4周，运动组坐骨神经运动传导速度高于模型组（P<0.05）。

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MNCV and SNCV of common peroneal nerve, sural nerve and median incision were examed by electromyography ( Danmark DISA2500C).

采用丹麦DISA2500C型肌电图仪测定腓总神经、腓浅神经、正中神经的运动神经传导速度（MNCV）及感觉神经传导速度（SNCV）。结果：所有结果以均值±标准差（（？）

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MNCV in LBP group was also lower than control group in8 weeks after operation.

术后8周时，运动神经传导速度恢复率低于对照组。

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Methods 25 patients with ulnar nerve injury and 25 healthy persons with similar age were studied, and the results of their MNCV between two groups were compared.

方法以25例尺神经损伤的男性患者作为患病组，同时选择25例健康男性作为对照组。

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The mixed nerve conduction velocity ( MNCV) was measured before and at the 2 nd, 4 th, 8 th week of administration with the tail nerve.

分别在0、2、4、8周末进行尾部混合神经传导速度的测定。

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The motor nerve conduction velocities ( MNCV) of the median nerve are less than38m/ s in four patients and two suspect patients.

4名确诊患者及2名疑似患者正中神经运动传导速度多在38m/s以下。

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Methods: The model rats suffering from diabetes were induced by streptozotocin ( STZ). 1 week after STZ injection diabetic rats were given Chinese herb or methylcobalamin. At the end of the experiment, MNCV of the sciatic were detected with evoked electromyogram.

方法：采用链脲佐菌素（STZ）诱发糖尿病大鼠模型，分别用益气活血方和弥可保进行治疗，用药4周后测定大鼠坐骨神经的运动神经传导速度（MNCV）。

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Conclusion Electrophysiological staging of cubital tunnel syndrome is mainly dependent on MNCV of ulnar nerve at the elbow. In mild, moderate and severe CUTS, MNCV is ≥ 45.0 m/ s,< 45.0 m/ s and < 40.0 m/ s respectively.

结论肘管综合征电生理的分期指标，主要看尺神经肘段的MNCV，MNCV≥45.0m/s提示为轻度，MNCV＜45.0m/s提示为中度，MNCV＜40.0m/s提示为重度。

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The sciatic nerve function index ( SFI), the motor nerve conduction velocity ( MNCV) and total myelinated axons per sight were counted on2 and4 weeks after the surgery.

术后2周及4周，观察坐骨神经功能指数、运动神经传导速度及单位视野有髓神经纤维计数。

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