1、

Clozapine, marketed in Australia since 1993, is an effective antipsychotic for the management of treatment-resistant schizophrenia.

氯氮平, 自从1993年在澳大利亚上市以来, 一直作为一种有效的抗精神病药物被用于治疗精神分裂症.

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2、

A boxed warning alerting prescribers to these reactions is included in the Product Information for clozapine.

医师们对于这些反应的警告已经列入氯氮平的产品说明中.

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3、

Parotid enlargement has previously been described in patients receiving clozapine.

以往曾有接受氯氮平治疗引起腮腺肿大的报告.

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4、

Mice given clozapine showed quadrupled AMPK actiity compared to actiity measured pre-drug.

鼠给药后显示AMPK活性是使用以前药物的四倍.

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5、

Objective To study the relationship between side-effect and EEG change by Clozapine.

目的研究氯氮平对脑电图的影响以及流涎、嗜睡与疗效的关系.

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6、

Mice given clozapine showed quadrupled AMPK activity compared to activity measured pre-drug.

鼠给药后显示AMPK活性是使用以前药物的四分之一.

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7、

The protein binding selectivity of clozapine was discussed.

讨论了氯氮平蛋白结合作用的选择性.

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8、

Objective : To investigate the misdiagnosis rate and the cause of the infection like syndrome ( ILS ) induced by clozapine.

目的: 调查氯氮平所致“类感染 综合征 ”的误诊发生率及原因.

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9、

Objectives : To compare the different effect of clozapine and chlorpromazine on serum salivary acid.

目的比较氯氮平和氯丙嗪对血清唾液酸的影响.

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10、

Conclusion The effect of clozapine had correlation with the EEG change , slavering and dizziness.

结论氯氮平疗效与脑电图异常、流涎、睡眠增多(包括嗜睡)程度呈反相关系.

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11、

Objective : To explore the effects of clozapine serum cholinesterase activity in schizophrenic patients.

目的: 探讨氯氮平对乙酰胆碱酯酶活性的影响.

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12、

Strong consideration should be given to ceasing clozapine while suspicious symptoms and signs are evaluated.

虽然症状还有待评估,但应考虑立即暂停使用氯氮平.

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13、

Increased saliva, abnormal EECG, constipation, decreased appetite or anorexy, tachycardia, abnormal ECG, dizziness or faint, lethargy and blurred vision in olanzapine group were greatly less than that in clozapine group. The difference was great and intensity of the difference was higher.

奥氮平组的唾液增多、脑电图异常、便秘、食欲减退或厌食、心动过速、心电图异常、头昏或昏厥、嗜睡、视力模糊,显著少于氯氮平组,差异有显著性,差异强度偏大。

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14、

Result The responses to clozapine for treatment refractory schizophrenic patients are positively related to the male but not related to the D4 receptor gene and other factors.

结果发现氯氮平的疗效与男性呈正相关,与D4受体基因及其它因素无明显相关。

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15、

Quantitative pharmaco EEG predicting the curative effect of clozapine in schizophrenia

定量药物脑电图预测氯氮平对精神分裂症的疗效

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