azole

Studies on~ 1h NMR of some azole compounds containing silicon

几类新型含硅唑类化合物~1H NMR研究

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Technique and Effect of Applying Multi-Effect Azole in Wheat Seed Dressing

小麦应用多效唑拌种技术与效果

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Methods: using 96 well microtiter trays as testing carriers, and ten twofold serial dilutions were made. The susceptibilities of 30 dermatophyte strains isolated from clinic to itraconazole and fluconazole, two new azole antifungal drugs, were determined.

方法：用96孔酶标板做药敏试验载体，10级倍比稀释药液，测定30株皮肤癣菌临床分离株对三唑类新药伊曲康唑和氟康唑的敏感性。

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Voriconazole is a second-generation azole antifungal agent that shows the characters of broad-spectrum and strong antibacterial, especially has good efficacy to the infection induced by invasive aspergillus.

伏立康唑（voriconazole）是第2代三唑类抗真菌药，具有抗菌谱广、抗菌效力强的特点，尤其对于侵袭性曲霉菌侵润所致感染疗效好。

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The Analyze of Drug Resistance and Study on Mechanisms of Fluconazole Resistance in Clinical Isolates of Candida Glabrata Fluconazole-resistant Candida Albicans Strains Exhibited Cross-resistance to Other Azole Antifungal Agents in Vitro

光滑假丝酵母菌耐药性分析及对氟康唑耐药机制研究氟康唑耐药的白念珠菌对唑类药物交叉耐药实验

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OBJECTIVE To improve the synthetic procedure of antipsychotic drug aripip-azole.

目的改进抗精神病药阿立哌唑的合成工艺.

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Practical Azole Corrosion Inhibitors for Copper and Its alloys

铜及其合金的实用唑类缓蚀剂

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Achievements on the Application of Hydrazine and Related Compounds for the Synthesis of Five-Membered Azole Heterocycles

肼类衍生物在五元唑类杂环合成中的应用进展

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We present here the crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121 in complex with the triazole drug fluconazole, revealing a new azole heme ligation mode.

我们提出了肺结核分支杆菌细胞色素P450CYP121与三氮唑类药物氟康唑的复合物的晶体结构，揭示了唑类与亚铁血红素新的结合模式。

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Therapeutic Effect of Four Azole Drugs in the Treatment on Tinea Manuum, Pedis, Corporis and Cruris

四种唑类药物外用治疗体股癣、手足癣的疗效观察

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OBJECTIVE: To analysis the marketing of azole antifungal agent during 2003~ 2005 so as to provide references for the research& development of this kind of drugs.

目的：分析2003年～2005年唑类抗真菌药的市场情况，以期对其研发生产及临床应用提供参考。

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Azole: a class of organic compounds having a five-membered heterocyclic ring with two double bonds.

氮杂茂: 一种由五种杂环元素,两组粘合剂组成的有机化合物.

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The susceptibility rates of 161 strains of yeastlike fungi to azole antifungals, such as fluconazole, itraconazole and ketoconazole were 95 7%, 94 4% and 85 1% respectively.

结果，161株酵母样真菌对唑类抗真菌药氟康唑、伊曲康唑、酮康唑的敏感率分别为95.7%、94.4%、85.1%。

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Progress of Azole Antifungal Agents

新唑类抗真菌药物研究进展

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Marketing of Azole Antifungal Agent During 2003~ 2005

2003年～2005年唑类抗真菌药市场分析

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Cloning and sequencing of the GTP cyclohydrolase ⅰ function region of azole target enzyme gene in artificially induced resistant Candida albicans

白念珠菌人工诱导耐药株唑靶酶三磷酸鸟苷环水解酶Ⅰ功能区的序列分析

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Based on the association with agricultural azole use, environmental sampling remains significant as well.

农业上对于唑类药物的应用，以及环境样品的监控也同样重要。

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Continued surveillance of azole resistance should be maintained to determine the resistance rates and any possible trend of increase in the isolation frequency of resistant strains.

对抗唑类药物的抗药率和分离耐药株频率的可能趋势应继续进行监控。

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Except terbinafine, Candida albicans strains were resistant to Azoles at different degrees, the non-Candida albicans resistence rates to Azole drugs were higher than Candida albicans.

除特比奈芬外，白假丝酵母菌和非白假丝酵母菌对唑类药物有不同程度的耐药，且非白假丝酵母菌的耐药率较高，二者差别有统计学意义。

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Three azole pesticide in the plant has shown unprecedented sterilization effect, make it have a lot use of space.

三唑类农药在植物杀菌方面表现出前所未有的效果，使得它有很大的使用空间。

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Synthesis and Antifungal Activity of N Azole Substituted Phenyl Ether Derivatives

氮唑取代苯基醚类衍生物的合成及其抗真菌活性

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Conventional diagnosis of aspergillosis is limited by poor culture yield, and so the true frequency of azole resistance has been unclear.

常规曲霉病诊断方法由于培养能力限制，不能准确测定对唑类药物的耐药水平。

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The azole antifungals including imidazoles and triazoles are the mainstay in clinical treatment of fungal infections.

唑类药物是治疗真菌感染的主要用药，按化学结构分为咪唑类和三唑类。

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26 azole compounds were synthesized, among them 22 compounds are firstly reported.

合成了26个二唑类与三唑类化合物，其中22个为新化合物。

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Azole and triazole drugs are cytochrome P 450 inhibitors widely used as fungal antibiotics and antimycobacterial actiity.

唑类和三氮唑类药物作为细胞色素P450抑制剂广泛被作为抗真菌药物和抗微生物药物使用.

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Observations on the sensitivity of Candida albicans isolates to azole drug in the renal transplant recipients

肾移植术后患者白念珠菌分离株的唑类药物敏感性观测

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Other azole antifungals such as itraconazole are substantially more expensive and do not have greater efficacy.

其他的吡咯类抗真菌药如伊曲康唑更加昂贵，且并不会有更好的效果。

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Objective : To develop the method for the determination of 4-methyl imid azole in caramel.

目的: 建立 4- 甲基咪唑的快速定量测定方法.

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The Synthesis of Azole and Tetrazine Compounds and Study on Corrosion Inhibition for Copper in NaHCO_3 Medium

唑类及嗪类化合物的合成及其在碳酸氢钠介质中对铜缓蚀性能的研究

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Among these four additives, only azole inhibitor X2 can reach the peeling strength target.

在这四种有机物中，只有唑类缓蚀剂X2可以达到剥离强度提高15%以上目标。

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