Radiation protection effects of sinapine on Drosophila melanogaster in a sex-linked recessive lethal test system

The results showed that there was no remarkable difference in body weight, relative organ weights, hematological indices, serum biochemical parameters and the histopathologic change of main organs between the median dose group or low dose group and the control group.

结果表明大鼠低、中剂量组的体重、脏器系数、血液学指标、血液生化指标、病理组织学检查等各项指标与对照组比较无显著性差异。

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26 patients in SRS group and 8 in FSRS group received external beam radiotherapy, and the median dose was 40 Gy and 30 Gy, respectively.

26例SRS和8例FSRS患者分别接受中位剂量为40Gy和30Gy的外照射。

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And the effect of median dose group of medical cactus polysaccharide and high dose group of edible cactus polysaccharide is very remarkable ( P < 0.01) compared with model group.

药用仙人掌多糖中剂量组及食用仙人掌多糖高剂量组效果显著（P<0.01）。

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The median dose to the organs at risk ( OAR) were as follows: spinal cord 9.46 ± 5.23Gy;

危险组织器官（OAR）平均剂量均值：脊髓（9.46±5.23）Gy；

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The dose of radiation was 44~ 56 GY, median dose was 50 GY. The chemotherapy scheme was CHOP.

化疗方案采用CHOP方案，放疗量44￣56GY，中位剂量50GY。

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But in median dose group only mild cloudy swelling in liver cells and focal haemorrhage in lung were observed.

病理检查高剂量组部分动物肝脏中度浊肿及水样变性和散在点状坏死，肺有散在性出血；

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The median dose was 46 Gy. Median follow-up period was 25 months ( range, 12-36 months).

中位照射剂量46Gy，中位随访期为25个月（12-36个月）。

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The study has provided theoretical basis in induced mutation medial lethal dose of different wheat varieties ( strains) to Ar+ implantation.

本项研究可为Ar+注入不同小麦品种（系）发生诱变的半致死剂量提供实验依据。

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Observe Single Leaf Asarum himalaicum's Acute Toxicity and Determination of its Median Lethal Dose

单叶细辛的急性毒性观察及半数致死量的测定

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The death ratios were observed and the median lethal dose ( LD 50) was calculated.

观察10d动物的存活情况，计算昆明小鼠单宁经口半数致死量（LD50）。

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Median lethal dose of toxicity tests was larger than 10g/ kg.

毒理学试验的半致死量均大于10g/kg；

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The estimation of median lethal dose or effective dose by an ordinary curve fitting method

曲线配合法在测定半数致死量上面的应用

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A Convenient Method for Calculating the Median Lethal Dose in Toxicity Testing

毒力测定中致死中量的简便计算方法

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Computer program calculating median lethal dose of drugs

药物半数致死量的计算程序

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Median lethal time, mean lifespan and mean maximum lifespan of drosophila fed with different concentration of ponceau 4R were lower than those in control groups dominantly ( P < 0.05 or P < 0.01) in survival experiment, and a dose-response relationship was shown.

生存试验中各浓度组雌雄果蝇的半数死亡时间、平均寿命及平均最高寿命均较对照组缩短（P<0.05或P<0.01），且存在剂量-反应关系。

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The median lethal time ( LT50) of the GV was shortened with the increase of the virus concentration and the decrease of the larval instar, during which the GV was fed.

幼虫饲毒后，致死中时（LT（50））随病毒浓度提高而缩短；随饲毒时虫龄的增大而延长。

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The median lethal time ( LT_ ( 50)) of P_ ( f) NPV to the larvae was shortened with the increase of the viral concentration.

各测试浓度下致死中时间（LT（50）为3.43-5.14天，随病毒浓度提高而缩短。

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The most virulent strain was screened out after evaluated by the indices of mortality, infection rate and the median lethal time ( LT50).

以桃蚜的校正死亡率、感染率及致死中时（LT（50））为指标综合评价不同菌株毒力。

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Conclusion Nano-hydroxyapatite has no accumulative toxicity to rabbits, it is suggested that it is safe when the hydroxyapatite-sol was applied intravenously as a drug carrier in small dosage more less than the medium lethal dose, even as a kind of anticancer drug.

结论纳米HAP在家兔无明显蓄积毒性，提示当用量远远小于最小致死剂量时，纳米HAP可作为药物载体，甚至在将来可能作为一种新型的抗癌药物，经静脉安全应用。

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The oral acute toxicity test showed LD50 ( medium lethal dose)> 5.5 g/ Kg. Such result demonstrates that the synthesized product is nontoxic according to the classification of acute toxicity standard.

通过对合成的产物进行急性经口毒性试验，发现其经口半数致死量（LD50，medium lethal dose）大于5.5g/Kg，按照急性毒性分级标准确定该依布硒林衍生物属实际无毒级。

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