The gut immune barrier dysfunction was caused by the decreasing of protein and sIgA contents. 5.

Objective To investigate the ability of repairing segmental bone defect with the compound of small intestinal submucosa and beta-tricalcium phosphate and small intestinal submucosa and to evaluate the feasibility to use them as bone substitute material.

目的观察研究小肠黏膜下层和β-磷酸三钙复合物（SIS/β-TCP）及小肠黏膜下层（SIS）修复骨缺损的能力，评估SIS作为骨支架材料的应用价值。

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Studies on small intestinal mucosa structural changes in nonalcoholic steatohepatitis

非酒精性脂肪性肝炎大鼠小肠黏膜结构变化的研究

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Objective To investigate the biocompatibility of small intestinal submucosa ( SIS) with cartilage cells and to explore the possibility of constructing tissue engineering cartilage with SIS as the scaffold and cartilage cells as the seed cells.

目的观察软骨细胞在兔小肠黏膜下层（SIS）上的生长特性，为使SIS作为软骨组织工程化的载体打下基础。

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Expression of Connexin-43 in Small Intestinal Mucosa of Human Fetus

Cx43在人胎早期小肠黏膜组织中的表达

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Binding Rule of Soybean Agglutinin to Small Intestinal Epithelia in Broiler

大豆凝集素与肉鸡小肠黏膜细胞结合规律的研究

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This study indicated that the supplementary level of selenium at 0.15 mg/ kg and zinc at 50 mg/ kg in diet should be an appropriate ratio which would keep the normal gut barrier function in the broiler.

结论：日粮中按锌50mg/kg、硒0.15mg/kg的比例添加，对于维持肠道黏膜的正常屏障结构是合适的。过高或过低的锌和硒对小肠黏膜有毒性作用，破坏其屏障功能；

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Objective To investigate the apoptosis of rat intestinal mucosal cell in cold restrain stress and explore the pathogenesis of its effects.

目的观察冷束缚应激（coldrestrainstress，CRS）状态下大鼠小肠黏膜细胞的凋亡情况；

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Uniaxial tensile mechanical properties of porcine SIS following different cross-linking treatments

两种交联处理后猪小肠黏膜下层单轴拉伸性能比较

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CONCLUSION: FK506 could induce a significant impairment of intestinal mucosa morphologically, which might be associated with up-regulated expression of iNOS and TNF-α in small intestinal mucosa.

结论：FK506通过上调iNOS和TNF-α的表达对小肠黏膜产生损伤，使小肠壁的通透性增加。

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Objective: To examine effects of n-butanol fraction from Fructus Kochiae ( NBFK) on gastric emptying of mice, α-glucosidase activities in rat intestinal mucosa, and glucose absorption in rat intestine as to elucidate the hypoglycemic mechanism.

目的：观察地肤子正丁醇部分（NBFK）对小鼠胃排空、大鼠小肠黏膜α葡萄糖苷酶活性及小肠糖吸收的影响，研究其降糖作用机制。

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Objective To investigate the feasibility and benefits of co-culture of cryopreserved islets with small intestinal submucosa ( SIS).

目的探讨猪小肠黏膜下层（SIS）对冷冻保存后大鼠胰岛细胞的支持和保护作用。

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Experimental Research of Porcine Small Intestinal Submucosa ( SIS) to Become Material of Lamellar Keratoplasty

猪小肠黏膜下层（SIS）作为板层角膜移植材料的实验研究

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Methods A model of hepatocirrhosis was made with CCL 4.The models were divided into model and electroacupuncture groups and a normal group was established as a control to observe hepatic, serous and intestinal glutathione ( GSH) contents and to quantitatively analyze the state of enteric mucosa.

方法用CCL4将模型组、电针组造成肝硬化模型，并与正常对照，观察肝组织、血清、肠道谷胱甘肽（GSH）含量并定量分析小肠黏膜状态。

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Conclusion Melatonin can protect small intestinal mucosa barrier through decreasing the shift of intestinal bacteria endotoxin, lowering cell factor level in plasma and inhibiting ICAM-1 expression in intestinal tissue after obstructive jaundice.

结论褪黑素通过减少肠道细菌内毒素的移位，降低血浆中细胞因子水平，抑制梗阻性黄疸后肠组织ICAM-1的表达，保护小肠黏膜屏障。

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In vivo tissue engineering& the application of small intestinal submucosa

体内组织工程技术&小肠黏膜下层的应用

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Objective To repair rat acute spinal cord injury by using the porcine small intestinal submucosa ( SIS) compound of Schwann cells.

目的应用复合雪旺细胞（SC）的小肠黏膜下层（SIS）修复大鼠急性脊髓损伤。

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Objective To review the research advance of the preparation and characteristics of small intestinal submucosa ( SIS).

目的追溯近年有关小肠黏膜下层（SIS）的制备及其特性的研究与进展。

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Results: Severe lesions in the jejunum and ileum were caused by indomethacin and the NO 、 MPO and MDA contents were markedly increased ( P < 0.05).

结果：消炎痛引起明显的小肠黏膜损伤，伴有NO、MPO、MDA含量增加及SOD活性下降（P<0.05，P<0.01）。

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The third toe of the left and right feet was chosen from 20 chicken respectively of autologous transplantation group and porcine small intestinal submucosa group, flexor digitorum profundus muscle tendon was cut off at middle phalanx, and 2 cm tendon defect model was created.

取自体移植组20只和猪小肠黏膜下层移植组20只鸡的左、右足第3趾，于中节趾骨处切断趾深屈肌腱并造成2cm的肌腱缺损模型。

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The Peyer's patches, mesenteric lymph node, intestinal mucosal epithelial tissues were prepared for the lymphocytes suspension and the changes of CD4+ and CD8+ T cells in these sites were determined by SABC immunohistochemistry;

分离Peyer's patches（PP结）、肠系膜淋巴结（MLN）、小肠黏膜上皮制备淋巴细胞悬液并涂片，用免疫细胞化学法检测CD4~+、CD8~+T细胞亚群；

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