Influence of Thiopurine Methyltransferase Activity on Pharmacokinetics of 6-mercaptopurine, Which is the Intermediate Metabolite of Azathioprine

1、

Objective To evaluate the efficacy of mycophenolate Mofetil ( MMF) and azathioprine ( AZA) after renal transplantation.

目的客观评价肾移植术后骁悉（mycohpenolatemofetil，MMF）与硫唑嘌呤（azathioprine，AZA）抗排斥反应效果的差别。

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2、

Treatment with immunosuppressants such as rituximab, azathioprine and cyclophosphamide resulted in a marked reduction in antibody levels and relapse rates.

免疫抑制剂治疗，如利妥昔单抗，硫唑嘌呤和环磷酰胺，明显减少抗体水平和复发率。

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3、

Thiopurine methyltransferase deficiency and azathioprine intolerance in autoimmune hepatitis

自身免疫性肝炎患者对硫唑嘌呤的耐受不良与硫代嘌呤甲基转移酶缺乏有关

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Efficacy of azathioprine combined with glucocorticoid on treatment of idiopathic retinal vasculitis The clinical observation of comprehensive therapy for idiopathic retinal vasculitis

硫唑嘌呤联合糖皮质激素治疗原发性视网膜血管炎特发性视网膜血管炎综合治疗的疗效分析

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5、

Background The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease are unknown.

背景在克罗恩病患者中，英夫利西单抗和硫唑嘌呤单药治疗或联合治疗的相对疗效和安全性尚未被了解。

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6、

Azathioprine and its potential metabolite inhibits adenosine kinase, diminish AMP formation by adenosine.

硫唑嘌呤及其有效代谢物抑制腺苷激酶（AK），使Ado转变AMP减少，从而增加Ado浓度。

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Raman Spectra and PL Spectra of Ganoderma lucidum SERS for Adsorption Behaviors of Azathioprine Molecules at Silver Surface

对不同地区灵芝特性的激光拉曼光谱表征硫唑嘌呤在银电极表面吸附的SERS光谱表征

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8、

A randomized, double-blind, controlled withdrawal trial in Crohn's disease patients in long-term remission on azathioprine

长期应用硫唑嘌呤的克罗恩病患者的随机、双盲、对照停药试验

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9、

RBC 6-TGN and hematological parameters in patients with Crohn's disease treated by azathioprine

接受硫唑嘌呤治疗的克罗恩患者的红细胞6-TGN水平和血液学参数

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10、

Study on the Redox Reaction of Azathioprine by Spectrofluorimetry

硫唑嘌呤氧化反应的荧光光谱法研究

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11、

OBJECTIVE To investigate the optimal condition to induce acute hepatic injury model in mice by azathioprine ( AZA).

[目的]探讨硫唑嘌呤（AZA）诱导小鼠制作急性肝组织损伤模型的最佳条件。

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Results Cyclosporine A, azathioprine and methylprednisolone were the baseline immunosuppression management.

结果术后常规给予环孢素A、硫唑嘌呤和甲基强的松龙三联免疫抑制剂。

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13、

Therapeutic Effects of High-dose Methylprednisolone Combined with Azathioprine on Immune Function in Patients with Myasthenia Gravis

甲基强的松龙与硫唑嘌呤联合治疗对重症肌无力临床和免疫功能的影响

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Clinical efficacy of azathioprine replaced with mycophenolate mofetil in renal transplant recipients

肾移植术后吗替麦考酚酯替换硫唑嘌呤的临床分析

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The influence of azathioprine on the pharmacokinetics of cyclosporine A in rabbits

硫唑嘌呤对环孢素A家兔药动学的影响

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16、

The treatment of Benazepril combined with Azathioprine for the IgA nephropathy

贝那普利联合硫唑嘌呤对IgA肾病的疗效观察

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17、

Comparison of clinical therapeutic effects of mycophenolate mofetil and azathioprine in patients after renal transplantation

肾移植病人应用霉酚酸酯与硫唑嘌呤的临床疗效比较

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Side Effect of Azathioprine on the Treatment of Myasthenia Gravis

硫唑嘌呤治疗重症肌无力副作用的研究

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19、

Fungi infection should be alerted when azathioprine is used for a long time.

长期应用需警惕合并真菌感染。

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20、

Toxic reaction and management of azathioprine in kidney transplantation recipients

肾移植后硫唑嘌呤的毒性反应及其治疗

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