1、

DNA methylation and its aberrance play an important role in the human development and tumorigenesis.

DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用.

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2、

So , it is possible that NAG 73 and the product act on the tumorigenesis of nasopharyngeal carcinoma.

NAG73可能可编码产物.该产物在鼻咽癌的发病发展中发挥作用.

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3、

The interaction of multiple genes plays an important role in tumorigenesis.

这些基因间的相互关系对肿瘤发生有重要意义.

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4、

Accordingly, it is believed that netrin-1 and its receptors may play an important role in tumorigenesis.

因此, netrin1 及其受体可能在肿瘤发生过程中发挥重要作用.

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5、

But the mechanism of the tumorigenesis of SV 40 Tag is not clear.

目前对SV40在肿瘤发生过程中所扮演的具体角色和确切机制还不十分清楚.

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6、

Gastric tumorigenesis is a complicated process involved a lot of steps and aberrant genes.

胃癌的发生发展是一个涉及多基因多步骤的复杂过程.

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7、

Angiogenin ( ANG ) can strongly stimulate blood vessel formation and play an important role in tumorigenesis.

血管生成素 ( angiogenin,ANG ) 是一个强有力的促血管生成因子,与肿瘤的发生、发展密切相关.

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8、

One is as a structural component of adherens junction, which forms the cadherin-catenin complex to mediate intercellular adhesion. The other is as a downstream effector of Wnt signaling pathway, which controls essential steps in many aspects of embryogenesis and tumorigenesis.

一是作为附着连接的组成部分,与钙粘蛋白结合形成复合体参与细胞间连接;二是作为信号分子,是Wnt信号途径的重要环节,在胚胎发育和肿瘤发生中起重要作用。

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9、

The structure, function of α actinin and its role in tumorigenesis were reviewed.

本文结合本实验室的研究工作,综述了α辅肌动蛋白家族成员的结构、功能及其与肿瘤发生的相关性。

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10、

If not repaired, the breakage can result in lethality or chromosome breakage, and if misrepaired, it can cause mutation, gene instability and the increased rate of tumorigenesis.

双链断裂得不到修复,细胞将会死亡或发生染色体断裂、丢失,若是错误修复将导致基因突变或基因组不稳定,增加癌症的风险度。

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