AEDS

METHODS: Two hundred and eighteen patients with refractory epilepsy were all treated with antiepileptic drugs ( AEDs )

方法: 218名癫痫病人,均为用过各种抗癫痫药物治疗效果不佳的难治性 癫痫.

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Objective To study the effect of varied thyroid hormones on antiepilepsy drugs ( AEDs).

目的探讨甲状腺素水平改变对抗癫痫药物（AEDs）治疗效果的影响。

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It is estimated that 30% epileptic patients fail to achieve good control with antiepileptic drugs ( AEDs) treatment.

大约30%的癫痫患者在应用抗癫痫药物后不能获得有效控制。

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Currently 74.77% epilepsy patients are using one AEDs; 23.32% patients are using combination therapy.

5.74.77%的癫痫患者目前采用的是单药治疗；23.32%的癫痫患者目前采用的是联合治疗。

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It is estimated that 30 % epileptic patients fail to achieve good control with antiepileptic drugs ( AEDs ) treatment .

大约30%的癫痫患者在应用抗 癫痫 药物后不能获得有效控制.

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Indexes of Detecting Changes of Bone in Children with AEDs Therapy

抗癫痫药物致儿童骨损害的常用检测指标

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Bad reaction were from mild to moderate, but it related to the dosage of AEDS.

不良反应轻至中度，但与合作AEDS的多少有关。

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In the long-term process, the side effects of AEDs are exposed.

在这一长期的治疗过程中，抗癫痫药物的副作用逐渐显露，尤其是对骨骼系统的不良反应自上世纪被发现以来正受到越来越大的关注。

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52.82% patients of single-drug treatment are using conventional AEDs.

采用单药治疗的癫痫患者中52.82%的患者使用的是传统抗癫痫药物，44.46%的患者使用的是新型抗癫痫药物。

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Objective To find out the relationship of obesity associated with different antiepileptic drugs ( AEDs) in epileptic children.

目的了解应用不同抗癫痫药（AEDs）所导致癫痫患儿肥胖的情况。

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AEDs responsiveness is good;

对抗癫痫药物的反应较好；

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Objective: To study the bone metabolism in patients with epilepsy after antiepileptic drugs ( AEDs) treatment.

目的：探讨抗癫痫药对癫痫患者骨代谢影响。

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Combined therapies of AEDs had lower retention rate.

抗癫痫药物联合治疗的保留率较低。

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Now 70-80 percent seizure can be controlled by the rational and scientific use of antiepileptics ( AEDs).

癫痫的治疗主要是用药物控制发作，合理科学地应用抗癫痫药物（Antiepileptics，AEDs），70%～80%癫痫患者可以得到控制。

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Conclusions Different AEDs have different effects on the neuropsychological function because of their different chemical structure and therapeutic mechanism.

结论抗癫痫药物的化学结构和作用机制不同，所以对认知功能的影响也不同；

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Methods The data of clinical and EEG features, head CT and MRI, results of AEDs treatment in 56 cases of children with BECCT were analysed.

方法分析56例BECCT临床发作形式、EEG表现、影像学及治疗资料。

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EEG may be atypical in some children administered AEDs.

曾接受AEDs治疗者EEG可能不典型.

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So doctor pay close attention to hepar or renal function damage caused by AEDs.

因此，近年来抗癫痫药物引起的肝肾功能损害越来越受到临床医生的关注。

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Expression and Regulatory of Cytochrome 450 enzymes and relation with AEDS

细胞色素P4503A基因表达调控及与抗癫痫药物的关系

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AEDs can raise concentrations of 5-HT/ 5-HIAA in CSF.

卡马西平能提高脑脊液及血浆中5-HT和5-HIAA含量。

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Objective To investigate the course of pregnancy and relative factors in pregnant women with epilepsy on administration of AEDs.

目的探讨抗癫痫药物在癫痫孕产妇中应用的相关因素。

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This patient and one other patient required immune-modulating therapy in addition to AEDs.

这病人和另外一名病人除了抗癫痫药物还需要免疫调节治疗。

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Objective To study the effects of antiepileptic drugs ( AEDs) on sex hormones in male epileptic patients.

目的研究抗痫药物（AEDs）对男性癫痫患者性激素水平的影响。

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Indubitably, most of the AEDs have side effects in varying degree.

不可否认抗癫痫药物都有不同程度的副作用。

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55.54% patients of combination therapy are using conventional AEDs and new AEDs. 6.

采用联合用药的癫痫患者中，55.54%的患者使用传统抗癫痫药物和新型抗癫痫药物，28.93%的患者使用传统抗癫痫药物和传统抗癫痫药物。

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Setting up fast and high-effective epilepsy models can provide us both ways to study the mechanism and new targets for AEDs screening.

建立快速、高效的癫痫动物模型不仅可以为癫痫的机制机理研究提供重要的方法和手段，还可以为新的AEDs的筛选提供有效的途径。

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The effect of morphine on the immunologic function of the traumatic rats and the survive of AEDs ascite carcinoma rats

吗啡对创伤小鼠免疫功能和艾氏腹水癌小鼠存活的影响

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102 were given the first-line anti-epilepsy drugs ( AEDs).

对照组102例，应用传统的一线抗癫痫药（AEDs）治疗。

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The frequency of intractable seizures after stopping AEDs in seizure-free children with epilepsy EVALUATION OF THE RISK FACTORS OF POSTTRAUMATIC EPILEPSY

无癫痫发作的癫痫患儿停药后难治性癫痫的发作频率168例儿童外伤性癫痫的临床分析

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Objective To explore the therapeutic efficacy of three kinds of antiepileptic drugs ( AEDs) and choose the ideal AEDs among them.

目的总结并探讨三种抗癫痫药（AEDs）的疗效，从而选取最佳的AEDs。

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