BPDE

  • BPDE
  • 释义

    [医][=broparoestrol]溴底乙苯;

纠错 数据更新时间:2024-12-23 00:06:40
1、

A comparative study on mutation by γ-radiation and BPDE was conducted in MSU-1 · 1 human fibroblasts at the hprt gene.

对γ射线和BPDE诱发人成纤维细胞株MSU-1·1bprt基因突变进行了比较研究。

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2、

Methods A549 cells cultured in vitro were divided into heat stress group and BPDE group.

方法体外培养的A549细胞分为高温应激组和BPDE组。

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3、

The content increase of 8-OH-dG was in accordance with the progress of cell carcinogenesis, which was displayed in human bronchial epithelial cells induced by BPDE and NiS.

在体外用BPDE和NiS作用于人支气管上皮细胞系诱导其转化和癌变过程中,8OH dG出现于细胞转化之前,其含量的增加与细胞癌变进程相一致。

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4、

The tumor was squamose carcinoma confirmed by histopathological examination. The culture system in this study provided a potential tool for studying the molecular mechanism of carcinogenesis of human bronchial epithelial cells induced by BPDE.

本实验以反式BPDE成功地诱发了人支气管上皮细胞恶性转化,为后期进一步研究其致癌的分子机制、寻找致癌相关基因提供了理想的生物学材料。

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5、

The changes of 8-OH-dG in the progress of carcinogenesis were detected in human bronchial epithelial cells induced by Benzo ( a) pyrene diol-epoxide ( BPDE) and sulfide nickel ( NiS) in vitro.

并利用苯并(a)芘代谢产物B(a)P二醇环氧化物(BPDE)和结晶型硫化镍(NiS)诱导的体外人支气管上皮细胞转化癌变模型,检测癌变进程中8OH dG的变化。

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6、

Mutation induced by  ̄( 60) Co γ-ray BPDE in msu-1 · 1 human fibroblast at the HPRT locus

~(60)Coγ射线和BPDE诱发人成纤维细胞hprt基因突变的研究

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7、

Conclusions Anti-BPDE can result in DNA strand breakage, and the degrees of damage is related to the administrated doses of anti BPDE.

结论反式BPDE可导致DNA断裂损伤,其损伤程度与剂量有一定关系。

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