antisense

Objective To observe the effect of telomerase antisense oligodexynucleotides on human gastric cancerous cell line.

目的:观察端粒酶反义寡聚脱氧核苷酸对人胃癌细胞株的作用.

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The sequencing result of antisense DNA fragment was in accordance with the known LMP 1 gene.

结果:酶切产物和PCR产物 的凝胶电泳显示400bp左右的目的基因片段,测序结果显示与已知LMP1基因序列一致.

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Antisense oligonucleotides have been successfully employed to inhibit and modulate specifically gene expression.

反义寡聚核苷酸已成功用于对基因表达的特异性调控与抑制.

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Liver-targeted gene delivery was often seen in antisense drugs.

基因肝靶向递送多见于反义药物.

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Antisense technique is an important area of research in cancer-associated treatment.

反义技术是目前癌症治疗领域很重要的一门技术.

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There was no effect of the control antisense oligonucleotide on lipoprotein levels or oxidative parameters.

使用反义核苷酸链安慰剂不会引起脂蛋白水平和氧化参数的改变.

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MMP-9 activity was assessed in supernatants from HBECs stably transfected with pEGFPc 1-antisense-ET-1 converting enzyme ( ECE ) RNA.

明胶聚丙烯酰胺凝胶电泳酶谱法检测稳定转染ET - 1转换酶 ( ECE ) 反义核酸上皮细胞培养上清MMP - 9酶活性.

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Objective To study antiviral effect of Lihposome-mediated antisense oligonucleotides COS-ASIN.

目的　研究脂质体介导的反义寡核苷酸在体外对乙型肝炎病毒基因复制和表达的抑制.

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Objective: In order to explore the effects of CD 40 antisense RNA on Balm cell.

目的: 探讨CD40反义RNA对Balm细胞的影响.

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Applying antisense oligonucleotide to block the expression of CLC-3 mRNA .

应用反义核酸的阻断CLC一 3mRNA 在细胞中的表达.

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ObjectiveTo investigate the influence of STAT 3 antisense oligodeoxynucleotides ( ASO-STAT 3 ) on radiosensitivity of B 16 cells.

目的探讨反义 STAT3 转染鼠恶性黑色素瘤B16细胞后,肿瘤细胞辐射敏感性的变化.

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Antisense conformational triggers based on molecular beacons can be used to initiate catalytic events.

基于分子信标的反义构象触发,能开启催化事件.

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Objective To estimate the effort between antisense RNA probe and random primed DNA probe.

目的比较不同方式标记非放射性探针的原位杂交效果.

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Result After A 549 was infected by recombinant retroviral vector expressing antisense ANG, ANG protein level decreased greatly.

结果　构建出含反义血管生成素的逆转录病毒载体,感染A549细胞后, 能有效抑制A549细胞血管生成素蛋白的表达.

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Until now, several methods have been developed to improve the intracellular delivery of antisense oligonucleotides.

到目前为止, 已发展了数种提高寡聚核苷酸类化合物细胞内转运的方法.

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