AIM: To investigate the effect of intracerebroventricular administration of streptozotocin ( STZ) on expression of A β in rat brain.

1、

Methods: Low dose injections of STZ were used to induce type I diabetes mellitus in the CMV-human Fas-ligand ( hFasL) transgenic mice.

方法利用hFasL转基因小鼠，用低剂量的链脲霉素（STZ）来诱导糖尿病。

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2、

Objective: To study the effects of Vanadate ( Va) on renal function, and structure in streptozotocin induced diabetic rats and to provide the experimental bases for clinical application of Va.

目的观察钒酸盐（Va）对链脲霉素诱导的糖尿病（DM）大鼠肾脏功能和结构的影响。

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3、

OBJECTIVE To observe the effect of rosiglitazone maleate on insulin sensitizing and blood lipid level of diabetic rats induced by streptozotocin.

目的观察罗格列酮对由链脲霉素引起的2型糖尿病大鼠模型的血清胰岛素、肝细胞胰岛素受体及血糖的影响。

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Methods: Diabetic rats established by abdominal injection of streprotozin ( 50mg/ kg) were taken as the model group.

方法腹腔注射链脲霉素（50mg/kg）制作糖尿病大鼠模型。

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MCE ( 14,28,56 mg/ kg) postponed the increase of the blood sugar level and decrease the peak sugar concentration of the rats after taking sucrose.

苦瓜素（14,28,56mg/kg）能降低链脲霉素诱发高血糖大鼠的血糖及HbA1C，能推迟大鼠口服蔗糖后血糖升高时间及降低血糖峰浓度。

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Methods 1. The diabetes Wistar rats were induced by intravenous administration of streptozotocin ( STZ) in a single dose of 60mg/ kg via penis dorsal vein.

【方法】1.采用链脲霉素（streptozotocin，STZ）60mg／kg尾静脉一次性注射法诱导建立Wistar大鼠Ⅰ型糖尿病模型。

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Results ① Islet graft primary nonfunction did not appear in any diabetic rats within the 4~ 7 days after injection of STZ, but appeared in all recipients without normal saline loading 9 days later after injection of STZ ( P < 0 01).

注射链脲霉素后9d以上时进行胰岛移植，在无生理盐水负荷的条件下，全部出现PNF，两者差异显著（P<001）。

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METHOD Normal mice, glucose induced hyperglycemic mice and streptozotocin ( STZ) induced diabetic mice were used in this study; The serum glucose concentrations were determined by method of glucose oxidase.

方法采用正常小鼠，葡萄糖致高血糖小鼠，链脲霉素（STZ）诱发的糖尿病小鼠，用葡萄糖氧化酶法测定血糖值。

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Objective: To observe Tangshen Fuyuan decoctions effect on DN rats due to STZ.

目的：观察糖肾复元汤对链脲霉素（STZ）糖尿病肾病大鼠的疗效。

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Diabetic models were induced by intravenous STZ injection in inbred lewis rats and en bloc transplantation of pancreas, duo(?) enum and kidney;

选用纯系Lewis大鼠，用链脲霉素诱导成糖尿病模型，在同系间成功地施行了全胰十二指肠肾脏整块联合移植，手术成功率82.6%。

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Methods Hyperglycemia model was made by intravenous injection of streptozocin in 44 SD rats.

方法采用44只SD大鼠尾静脉注射链脲霉素的方法，建立超负荷血糖模型。

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· AIM: To study the expression of β-catenin in streptozotocin ( STZ)-induced diabetic rat retina and the possible relevance of β-catenin in the early stage of STZ-induced diabetic retinopathy.

目的：探讨链脲霉素（Streptozotocin，STZ）诱导的糖尿病鼠视网膜β-连环蛋白（β-catenin）表达以及与早期糖尿病视网膜病变发展的可能关系。

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13、

Aortic Collagen Nonenzymatic Glycosylation Level in Streptozotocin-induced Diabetic Rats

链脲霉素所致糖尿病大鼠主动脉胶原非酶糖化的观察

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Anti-diabetic effects of extractives of Marine algae in streptozotocin-induced diabetic rats

海藻提取物对链脲霉素糖尿病大鼠的降血糖作用

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The inhibitory activity of PL-AG against lipid peroxidation in diabetic rats was higher than that of AG.

PL-AG比AG更有效的抑制链脲霉素糖尿病大鼠体内脂质过氧化。

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Diabetes was induced by a single injection of streptozotocin ( STZ). The form of diabetes mellitus induced by parenteral STZ administration in rats is insulin-dependent ( type I).

糖尿病模型由一次性注射链脲霉素（STZ）获得，通过注射STZ获得的糖尿病模型是胰岛素依赖型糖尿病，即一型糖尿病。

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Method: Using chemicals streptozotocin prep rats diabetes model; to measure rats blood-sugar content with glucose oxidase method;

方法：采用化学药品链脲霉素（streptozotocin）制备小鼠糖尿病模型，用葡萄糖氧化酶法测小鼠血糖含量。

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18、

Evaluation of an aldose reductase inhibitor on lens metabolism, ATPases and antioxidative defense in streptozotocin-diabetic rats: an intervention study

醛糖还原酶抑制剂对链脲霉素糖尿病小鼠眼晶状体代谢影响、ATP酶及抗氧化性防御的评价：一项干预性研究

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Methods Female Wistar rats were injected a low dose of streptozotocin ( 30mg/ kg) intraperitoneally followed by a high fat high fructose diet and drank 10% fructose water.

方法腹腔注射小剂量链脲霉素（streptozotocin，STZ），30mg/kg轻度损伤胰岛β细胞，造成大鼠糖耐量异常后加喂高果糖高脂肪饲料，并饮用10%果糖水，造成胰岛素抵抗。

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Streptozocin induced hyperglycemia significantly inhibited amygdala kindling development ( p0.01).

链脲霉素引起的高血糖抑制大鼠杏仁核点燃发展进程（p0.01）。

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