telomere

Telomere is at the end of the chromosome in eukaryotic cells and protects chromosomes.

摘要端粒位于真核细胞染色体末端,起保护染色体末端的作用.

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Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.

结论端粒缩短并激活端粒酶是涎腺肿瘤形成的重要因素.

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ALT and TA mechanisms are dominant maintenance mechanisms of the telomere length.

端粒长度的维持机制主要有ALT机制和TA机制.

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Telomere locates on the terminal of DNA containing repeat DNA sequence.

端粒是位于染色体末端的串联重复核苷酸序列.

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Objective To evaluate the role of telomere and DCC in tumor transformation and progression.

目的　分析端粒长度及DCC基因 mRNA 表达在大肠癌及腺瘤发生发展中的作用.

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Telomerase system is the genetic name of telomerase and telomere.

端粒酶系统是端粒和端粒酶的总称.

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Researchers estimate that telomere maintenance activity occurs in about 90 % of human cancers.

研究人员估计,90%的癌症中端粒一直处于活跃状态.

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Considering the risks of telomere-extension therapy, he thinks that scientists have bigger fish to fry.

因为延长端粒疗法具有危险, 他认为还有更大的问题需要科学家去解决.

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The telomere is like a cellular clock, because every time a cell divides, the telomere shortens.

端粒就像是细胞的时钟, 因为在每次细胞分裂时它都首先要缩短.

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Overall, the study participants had an average telomere loss of 21 nucleotides ( structural units ) per year.

总的来说, 该项研究的参与者每年平均损失21个核甘酸 ( 结构单位 ).

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Therefore, TRF 2 may protect chromosome ends by maintaining the correct structure at telomere termini.

因此, TRF2可保护染色体末端保持正确的结构,端粒末端.

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Can telomere maintenance be eliminated effectively ( and selectively ) enough by more tractable approaches?

端粒维持可以由足够有效地 ( 或选择性地 ) 更易控制的途径而有效地被排除 吗 ?

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We summarize the present research of telomerase and telomere and their applications on ocular disease.

在此,我们就端粒、端粒酶研究现状及其与眼科疾病的关系和应用进展作一综述.

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