1、

This review concentrates on drug-resistance mechanisms of taxanes that include drug target change, avidity change between drug-target interaction, decrease of cellular effective drug concentration, downstream cellular responses to a drug target molecular lesion, and cell cycle regulation-mediated drug resistance.

该文作者就其耐药机制的研究进展,分别从药物靶点及靶点与药物的亲和力改变、细胞内有效药物浓度降低、药物靶分子下游效应信号途径异常、细胞周期调控等方面作如下综述。

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Objective To investigate the effects of Anti-vertigo granule ( AVG) on vertigo and related pathological factors with the lesion clinically and experimentally.

目的研究抗晕平(颗粒)冲剂(KYPCJ)对血瘀动物模型眩晕相关因素的作用,并观察该药对眩晕临床的疗效。

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Treatment of Ischemic Optic Disc Lesion with Oxygenated Blood Autotransfusion following Ultraviolet Radiation

紫外线照射充氧自体血回输治疗缺血性视神经乳头病变的疗效观察

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Effect of electroacupuncture stimulation on autotomy and nerve regeneration after sciatic nerve lesion in rats

电针刺激穴位对大鼠神经损伤后自残及神经再生的影响

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Patients and Methods: Patients with advanced SCCHN who were refractory to standard therapies and who had at least one assessable and accessible lesion were enrolled.

研究方法和对象:晚期的SCCHN患者,并且能耐受标准的化疗,而且至少有一次疗效评价和能耐受的肿瘤负荷。

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Cytology diagnosis of ASCUS patients, HPV-positive lesion detection rate higher than the highly negative.

细胞学诊断为ASCUS的患者中,HPV阳性者高度病变检出率高于阴性者。

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Conclusion The kidney lesion in non arytenoid persons with changed Bp nyctohemeral rhythm is more severe than the arytenoid.

结论血压昼夜节律改变呈非杓型者其肾损害较杓型者严重。

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Objective To study the relationship between synovial membrane apoptosis and different arthropathy for the pathogenesis of cartilage lesion in arthropathy.

目的:研究滑膜凋亡与不同关节病变的关系,并探讨病理关节软骨损害的机制。

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The retention of mineral is of relevance for lesion arrestment or remineralization of early root caries.

保留龋损区的矿物质对于预防胶原纤维的降解、促进早期根面龋的再矿化是非常重要的。

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Long lesion, imcomplete stent expansion, imcomplete apposition and drug-eluting stents.

长病变,支架贴壁不好,支架没有完全覆盖病变,使用药物涂层支架;

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Objective: To observe aorta lesion in type 2 diabetes patients.

目的:观察2型糖尿病患者的大动脉病变情况。

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Antiulcer activities of acetyl-glutamine Zinc on Gastric lesion models

乙酰谷氨酰胺锌抗实验性胃溃疡的作用研究

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Conclusion It is effective in therapy of anti-tuberculosis drugs liver lesion.

结论GSH对治疗抗结核药物性肝损有效。

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Conclusions Deficiency of Se and VE and increase the expression of TGF-β 1 mRNA, and it may be one of reasons of anoxemic myocardium necrosis and brain tissues lesion related with peripheral characteristic.

以Se和VE联合缺乏变化最显著。结论Se和VE缺乏可诱导大鼠心脑组织TGF-β1mRNA表达上调,是缺血缺氧性心肌坏死和脑组织损伤的原因之一。

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In their experiments, the scientists gae anesthetized rats a range of spinal cord injuries to lesion or kill motor neurons or performed sham surgeries.

在他们实验中科学家使麻醉的大鼠脊髓受到不同程度的伤害:使神经受损伤或者破坏神经元或者实施脊髓损害手术。

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Effect of Sanhuang tincture to treat patients with anabiotic exudation skin lesion

三黄酊治疗糜烂渗出面皮肤损伤的疗效观察

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The common adverse reactions in clinic are hepar and renal functional lesion 、 cordis damage 、 bone marrow depressions anaemias alopecia and infecting et al.

临床上常见的副作用有,胃肠道反应,肝肾功能损害、心脏损害,骨髓抑制、贫血、脱发、感染等。

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If you have a complete lesion of the spinal cord, you cannot move because your brainstorms cannot reach your muscles.

如果你的脊髓完全损伤,你无法运动因为你的脑电风暴无法将信号发送到你的肌肉中。

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Focal nodular hyperplasia ( FNH ) of liver is a benign lesion that is often asymptomatic.

局限性结节 增生 是一良性肝脏病杜,临床上常无症状,约占原 发性 肝肿瘤的8%.

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